منابع مشابه
Uric acid: neuroprotective or neurotoxic?
Uric Acid: Neuroprotective or Neurotoxic? To the Editor: A decades-old scientific dispute pits “as a pro-oxidant, uric acid causes disease”1–3 against “uric acid is an important antioxidant.”2–6 The antioxidant properties of urate are long-known.6 However, arguably, this issue per se originated in our complimentary reports of urate as both a primate evolutionary substitute for ascorbate4 (a put...
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Chronic marijuana intake was known to induce morphological changes to the brain impairing memory and learning ability. However, several studies demonstrated the protective effect of marijuana post-brain traumas. This article reviews studies that strengthen our horizon to understand the effects of marijuana smoking in brain. This review predicts that optimum use of marijuana or pure marijuana co...
متن کاملZinc supplementation: neuroprotective or neurotoxic?
While zinc is essential for normal brain function and repair, recent work has implicated this trace element in the neuronal damage and death that follow traumatic brain injury, stroke, and seizure. Therefore, the development of new zinc-based therapeutic strategies will need to consider the emerging roles of zinc in the central nervous system.
متن کاملAre volatile anesthetics neuroprotective or neurotoxic?
Volatile anesthetics are one class of the most commonly used drugs. However, the mechanisms for these drugs to induce anesthesia are not fully understood and have been under intensive investigation. Two other effects of these anesthetics on the central nervous system, volatile anesthetics-induced neuroprotection and neurotoxicity, currently are hot research fields. Although data from animal stu...
متن کاملA systematic review of existing data on long-term lithium therapy: neuroprotective or neurotoxic?
Lithium is an efficacious agent for the treatment of bipolar disorder, but it is unclear to what extent its long-term use may result in neuroprotective or toxic consequences. Medline was searched with the combination of the word 'Lithium' plus key words that referred to every possible effect on the central nervous system. The papers were further classified into those supporting a neuroprotectiv...
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ژورنال
عنوان ژورنال: Stroke
سال: 2008
ISSN: 0039-2499,1524-4628
DOI: 10.1161/strokeaha.107.513242